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GHK-Cu is a naturally occurring copper-binding tripeptide investigated for collagen signaling, skin remodeling, wound repair, antioxidant activity and hair/skin biology. Its strongest human experience is topical rather than injectable.
Topical copper-peptide studies have generally reported good tolerability, but that does not establish the safety of injected or systemic GHK-Cu. Systemic adverse effects, long-term exposure and dose-response safety are not well characterized for unapproved research formulations.
Laboratory and topical research has reported effects on collagen, extracellular-matrix remodeling and tissue repair. A controlled study after laser resurfacing found overall skin improvement in participants, but the copper-tripeptide arm was not significantly better than the comparator.
Additional commentary from Dr. Dean Jones, DC. This video is embedded for context and education; WILGO does not control or independently verify claims made in third-party videos.
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